CAPN9

Across TCGA cell cohorts, CAPN9 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,452 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible CAPN9-associated GO terms across cancer lineages are Peptidyl-lysine oxidation, Regulation of somitogenesis, and Receptor-mediated endocytosis of virus by host cell. Each is linked with CAPN9 in more than 7 cancer types. Because this analysis shows association rather than direction, both CAPN9-to-partner and partner-to-CAPN9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-lysine oxidation grouped by CAPN9-low versus CAPN9-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPN9→partner) and Y-score (partner→CAPN9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Peptidyl-lysine oxidation →	-1.517	-0.294	<.001	.003	3	8
BREAST	Regulation of somitogenesis →	+1.223	+1.290	<.001	<.001	3	7
BREAST	Receptor-mediated endocytosis of virus by host cell →	-0.250	-1.263	<.001	<.001	3	7
BREAST	Regulation of atrial cardiac muscle cell membrane repolarization →	-0.270	-1.496	<.001	<.001	3	7
BONE	Acetylcholine biosynthetic process →	+1.317	+0.362	.001	.004	3	7
BREAST	Amelogenesis →	-0.210	-1.819	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,452 associations by consensus.

Peptidyl-lysine oxidation by CAPN9 expression — BONE

Explore this box plot interactively →