Across TCGA patient cohorts, CAPN8 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,419 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CAPN8-associated proteins across cancer lineages are TJP3_S203, TJP3_S346, and PLS1. Each is linked with CAPN8 in more than 5 cancer types. Because this analysis shows association rather than direction, both CAPN8-to-partner and partner-to-CAPN8 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPN8→partner) and Y-score (partner→CAPN8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TJP3_S203 →	+1.118	+1.582	<.001	<.001	3	6
HNSC	TJP3_S346 →	+0.700	+1.169	<.001	<.001	3	6
PDAC	PLS1 →	+0.580	+1.380	<.001	<.001	3	6
PDAC	PLEKHA6 →	+0.483	+1.285	<.001	<.001	3	6
LUAD	MISP3_S91 →	+0.751	+1.405	<.001	<.001	3	6
BRCA	MLPH →	+0.965	+2.549	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,419 associations by consensus.

Exploration

CAPN8 survival (RNA) · tumor vs normal (RNA) · all CAPN8 data types