Across TCGA patient cohorts, CAPN8 mutation is significantly associated with the RNA expression of many other genes, with 1,441 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CAPN8-associated genes across cancer lineages are RN7SL440P, MIR4418, and NDUFB8P1. Each is linked with CAPN8 in more than 1 cancer types. Because this analysis shows association rather than direction, both CAPN8-to-partner and partner-to-CAPN8 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPN8→partner) and Y-score (partner→CAPN8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	RN7SL440P →	+0.284	+5.108	<.001	.008	3	2
COAD	MIR4418 →	+0.918	+4.893	<.001	.005	3	2
LIHC	NDUFB8P1 →	+0.198	+5.544	<.001	.004	3	1
UCEC	CCL5 →	+1.156	+2.158	<.001	<.001	3	1
UCEC	LINC01607 →	-0.685	-4.066	<.001	<.001	3	1
UCEC	MESTIT1 →	-0.194	-2.137	.002	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,441 associations by consensus.

Exploration

CAPN8 survival (RNA) · tumor vs normal (RNA) · all CAPN8 data types