CAPN8

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CAPN8 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,832 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible CAPN8-associated GO terms across cancer lineages are Establishment of epithelial cell apical/basal polarity, AV node cell to bundle of His cell communication by electrical coupling, and Protein transport within lipid bilayer. Each is linked with CAPN8 in more than 9 cancer types. Because this analysis shows association rather than direction, both CAPN8-to-partner and partner-to-CAPN8 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPN8→partner) and Y-score (partner→CAPN8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PANCREASEstablishment of epithelial cell apical/basal polarity →-0.205-3.018<.001<.001310
STOMACHAV node cell to bundle of His cell communication by electrical coupling →-1.416-4.036<.001<.001310
LUNG_NSCLC_LUADProtein transport within lipid bilayer →+0.380+3.222<.001<.00139
URINARY_TRACTRegulation of cytotoxic T cell degranulation →+1.678+2.337<.001.00139
URINARY_TRACTNegative regulation of cytotoxic T cell degranulation →+1.678+2.337<.001.00139
LIVERPeptidyl-lysine oxidation →-1.139-1.615<.001.00739
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,832 associations by consensus.

Exploration