CAPN7

Across TCGA cell cohorts, CAPN7 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,468 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CAPN7-associated GO terms across cancer lineages are Regulation of microtubule-based process, P-body assembly, and Negative regulation of transcription by RNA polymerase III. Each is linked with CAPN7 in more than 13 cancer types. Because this analysis shows association rather than direction, both CAPN7-to-partner and partner-to-CAPN7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of microtubule-based process grouped by CAPN7-low versus CAPN7-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPN7→partner) and Y-score (partner→CAPN7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Regulation of microtubule-based process →	+0.056	+0.669	<.001	<.001	3	14
LUNG_SCLC	P-body assembly →	+0.121	+0.574	.001	.001	3	14
UPPER_AERODIGESTIVE_TRACT	Negative regulation of transcription by RNA polymerase III →	+0.132	+0.988	<.001	<.001	3	13
BLOOD_Lymphoma	Adiponectin-activated signaling pathway →	+0.093	+0.646	<.001	<.001	3	13
STOMACH	Positive regulation of pinocytosis →	+0.130	+0.686	<.001	<.001	3	13
BLOOD_Myeloma	Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay →	+0.091	+0.921	<.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,468 associations by consensus.

Regulation of microtubule-based process by CAPN7 expression — BLOOD_Leukemia

Explore this box plot interactively →