CAPN6

Across TCGA patient cohorts, CAPN6 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,765 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CAPN6-associated proteins across cancer lineages are BDH2, NFIB, and PPP1R12B. Each is linked with CAPN6 in more than 4 cancer types. Because this analysis shows association rather than direction, both CAPN6-to-partner and partner-to-CAPN6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CAPN6 versus BDH2 in HNSC, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPN6→partner) and Y-score (partner→CAPN6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	BDH2 →	+0.555	+1.296	<.001	<.001	3	5
HNSC	NFIB →	+0.667	+1.442	<.001	<.001	3	4
HNSC	PPP1R12B →	+0.517	+0.685	<.001	.006	3	4
HNSC	ANK2 →	+0.435	+1.068	<.001	<.001	3	4
LUAD	RAB4A →	+0.336	+0.851	<.001	<.001	3	4
HNSC	EIF4G1 →	-0.203	-0.951	<.001	.007	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,765 associations by consensus.

CAPN6 vs BDH2 — HNSC

Explore this scatter interactively →