CAPN6

Across TCGA patient cohorts, CAPN6 protein abundance is significantly associated with the RNA expression of many other genes, with 10,793 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CAPN6-associated genes across cancer lineages are CRB3, ACY3, and MRAP2. Each is linked with CAPN6 in more than 3 cancer types. Because this analysis shows association rather than direction, both CAPN6-to-partner and partner-to-CAPN6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CAPN6 versus CRB3 in UCEC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPN6→partner) and Y-score (partner→CAPN6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CRB3 →	+1.262	+0.806	<.001	.003	3	3
UCEC	ACY3 →	+1.323	+1.276	.001	<.001	3	3
UCEC	MRAP2 →	+1.476	+1.157	.001	<.001	3	3
UCEC	PCTP →	+0.450	+0.804	<.001	<.001	3	3
UCEC	CHDH →	+1.407	+1.420	<.001	<.001	3	3
BRCA	NDRG2 →	+1.294	+0.700	<.001	.005	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,793 associations by consensus.

CAPN6 vs CRB3 — UCEC

Explore this scatter interactively →