CAPN15

Across TCGA pan-cancer cohorts, CAPN15 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated CAPN15 data layer compared with 24 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher CAPN15 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated CAPN15 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LUAD show a favorable association.

UCEC and LUAD are the cancer types where CAPN15 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Tertile	All	0.968	0.825	.032	2	view →
LUAD	DFS	Median	All	0.807	0.518	.047	1	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

CAPN15–UCEC (OS)

Open the UCEC breakdown →