Across TCGA pan-cancer cohorts, CAPN14 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated CAPN14 data layer compared with 18 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher CAPN14 Mutation is associated with better overall survival. In most high-consensus cancer types, elevated CAPN14 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCEC and ACC are the cancer types where CAPN14 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	All	0.968	0.657	.023	8	view →
ACC	DFS	Median	All	0.195	0.748	.003	3	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: CAPN14 tumor-vs-normal RNA expression · all CAPN14 data types