CAPN13

Across TCGA patient cohorts, CAPN13 protein abundance is significantly associated with the RNA expression of many other genes, with 6,868 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CAPN13-associated genes across cancer lineages are CYP4X1, TMC5, and CEACAM5. Each is linked with CAPN13 in more than 3 cancer types. Because this analysis shows association rather than direction, both CAPN13-to-partner and partner-to-CAPN13 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CAPN13 versus CYP4X1 in OV, with a Pearson correlation of 0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPN13→partner) and Y-score (partner→CAPN13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CYP4X1 →	+2.138	+1.147	<.001	<.001	3	4
LSCC	TMC5 →	+1.476	+0.929	<.001	<.001	3	4
UCEC	CEACAM5 →	+2.087	+1.102	.001	<.001	3	4
BRCA	INPP4B →	+1.625	+0.846	<.001	<.001	3	4
LUAD	CATSPERB →	+1.241	+0.796	.001	.002	3	4
LUAD	TC2N →	+1.026	+1.154	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,868 associations by consensus.

CAPN13 vs CYP4X1 — OV

Explore this scatter interactively →