CAPN12

Across TCGA cell cohorts, CAPN12 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,751 significant associations in total. KIDNEY shows the largest number of these associations.

The most reproducible CAPN12-associated GO terms across cancer lineages are Autophagosome membrane docking, [4Fe-4S] cluster assembly, and Cilium or flagellum-dependent cell motility. Each is linked with CAPN12 in more than 7 cancer types. Because this analysis shows association rather than direction, both CAPN12-to-partner and partner-to-CAPN12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Autophagosome membrane docking grouped by CAPN12-low versus CAPN12-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPN12→partner) and Y-score (partner→CAPN12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Autophagosome membrane docking →	+0.114	+1.520	.001	<.001	2	8
KIDNEY	[4Fe-4S] cluster assembly →	-0.116	-2.053	<.001	<.001	3	7
OVARY	Cilium or flagellum-dependent cell motility →	-0.064	-1.408	.002	.002	2	7
KIDNEY	Flagellated sperm motility →	-0.106	-3.030	<.001	<.001	3	6
LIVER	Positive regulation of nitric oxide biosynthetic process →	+0.152	+1.251	.002	.002	3	6
STOMACH	Sterol homeostasis →	+0.068	+1.817	.002	.005	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,751 associations by consensus.

Autophagosome membrane docking by CAPN12 expression — OVARY

Explore this box plot interactively →