CAPN11

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CAPN11 protein abundance is significantly associated with the RNA expression of many other genes, with 2,675 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CAPN11-associated genes across cancer lineages are H2AC9P, BLZF2P, and RN7SL265P. Each is linked with CAPN11 in more than 2 cancer types. Because this analysis shows association rather than direction, both CAPN11-to-partner and partner-to-CAPN11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CAPN11 versus H2AC9P in LUAD, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPN11→partner) and Y-score (partner→CAPN11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADH2AC9P →+1.500+0.482<.001<.00133
CCRCCBLZF2P →-0.492-0.313.006.00133
OVRN7SL265P →-0.362-0.524.009.00432
LUADRFC3 →+0.387+0.403.001.00532
CCRCCTSC22D3 →+0.875+0.250.002.00732
LUADCD1C →-1.018-0.496<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,675 associations by consensus.

CAPN11 vs H2AC9P — LUAD

Per-sample scatter of CAPN11 vs H2AC9P in LUAD (Pearson r = 0.35).

Explore this scatter interactively →

Exploration