CAPN11

Across TCGA cell cohorts, CAPN11 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,216 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CAPN11-associated GO terms across cancer lineages are Glial cell differentiation, Branching involved in ureteric bud morphogenesis, and Golgi to plasma membrane transport. Each is linked with CAPN11 in more than 5 cancer types. Because this analysis shows association rather than direction, both CAPN11-to-partner and partner-to-CAPN11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Glial cell differentiation grouped by CAPN11-low versus CAPN11-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPN11→partner) and Y-score (partner→CAPN11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Glial cell differentiation →	+0.029	+0.547	.004	.006	3	6
UPPER_AERODIGESTIVE_TRACT	Branching involved in ureteric bud morphogenesis →	-0.062	-0.086	.004	.004	3	5
BREAST	Golgi to plasma membrane transport →	+0.084	+0.268	<.001	.007	3	5
BLOOD_Lymphoma	Biological process involved in interaction with host →	+0.070	+0.151	<.001	<.001	3	4
UPPER_AERODIGESTIVE_TRACT	Vacuolar transport →	+0.045	+0.080	.001	.009	3	4
UPPER_AERODIGESTIVE_TRACT	Vesicle-mediated transport to the plasma membrane →	+0.063	+0.097	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,216 associations by consensus.

Glial cell differentiation by CAPN11 expression — BLOOD_Leukemia

Explore this box plot interactively →