CAPN1

Across TCGA patient cohorts, CAPN1 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,337 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CAPN1-associated proteins across cancer lineages are ESRP2, SSH3, and CDC42BPG_S1482. Each is linked with CAPN1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CAPN1-to-partner and partner-to-CAPN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CAPN1 versus ESRP2 in UCEC, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPN1→partner) and Y-score (partner→CAPN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ESRP2 →	+0.431	+0.583	<.001	<.001	3	5
LSCC	SSH3 →	+0.442	+0.599	<.001	<.001	3	5
LSCC	CDC42BPG_S1482 →	+0.646	+0.610	<.001	<.001	3	5
HNSC	ZDHHC5 →	+0.253	+0.634	.006	.005	3	4
LUAD	PKP3 →	+0.475	+0.519	<.001	<.001	3	4
OV	CAPNS1 →	+0.366	+0.583	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,337 associations by consensus.

CAPN1 vs ESRP2 — UCEC

Explore this scatter interactively →