CAPN1

Across TCGA patient cohorts, CAPN1 protein abundance is significantly associated with the RNA expression of many other genes, with 17,026 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CAPN1-associated genes across cancer lineages are KIF14, SKA1, and RAD51AP1. Each is linked with CAPN1 in more than 6 cancer types. Because this analysis shows association rather than direction, both CAPN1-to-partner and partner-to-CAPN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CAPN1 versus KIF14 in GBM, with a Pearson correlation of -0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPN1→partner) and Y-score (partner→CAPN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	KIF14 →	-0.974	-0.197	<.001	<.001	3	7
GBM	SKA1 →	-0.862	-0.225	<.001	<.001	3	7
GBM	RAD51AP1 →	-0.815	-0.181	<.001	<.001	3	6
HNSC	NUP155 →	-0.695	-0.199	<.001	.001	3	6
GBM	BRIP1 →	-0.943	-0.224	<.001	<.001	3	6
LSCC	CCDC150 →	-0.803	-0.282	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,026 associations by consensus.

CAPN1 vs KIF14 — GBM

Explore this scatter interactively →