CAPG

Across TCGA pan-cancer cohorts, CAPG mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CAPG data layer compared with 21 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher CAPG mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated CAPG expression acts as an unfavorable survival marker, although some lineages such as PDAC and HNSC show a favorable association.

CCRCC, GBM, and PDAC are the cancer types where CAPG mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Tertile	All	0.702	0.949	.005	20	view →
GBM	OS	Quartile	All	0.380	0.713	.003	9	view →
PDAC	OS	Quartile	All	0.591	0.380	.046	4	view →
HNSC	OS	Median	III,IV	1.000	0.484	.038	4	view →
LSCC	DFS	Median	II,III,IV	0.972	0.875	.014	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CAPG–CCRCC (DFS)

Open the CCRCC breakdown →