CAPG

Across TCGA patient cohorts, CAPG mutation is significantly associated with the RNA expression of many other genes, with 1,251 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CAPG-associated genes across cancer lineages are RNA5SP413, RNA5SP423, and RNA5SP414. Each is linked with CAPG in more than 1 cancer types. Because this analysis shows association rather than direction, both CAPG-to-partner and partner-to-CAPG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP413 grouped by CAPG-low versus CAPG-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPG→partner) and Y-score (partner→CAPG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP413 →	+1.225	+2.084	<.001	.006	3	2
LUSC	RNA5SP423 →	+0.863	+6.733	<.001	<.001	3	2
UCEC	RNA5SP414 →	+0.498	+2.670	.001	.001	3	2
UCEC	RNU2-61P →	+0.283	+3.162	.008	.001	3	2
UCEC	LINC01047 →	+0.136	+2.122	<.001	.005	3	2
UCEC	RNA5SP419 →	+0.716	+2.884	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,251 associations by consensus.

RNA5SP413 by CAPG expression — UCEC

Explore this box plot interactively →