CAPG

Across TCGA cell cohorts, CAPG RNA expression is significantly associated with the go_rna of many other GO terms, with 4,255 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CAPG-associated GO terms across cancer lineages are Regulation of actin polymerization or depolymerization, Negative regulation of actin filament depolymerization, and Actin filament capping. Each is linked with CAPG in more than 16 cancer types. Because this analysis shows association rather than direction, both CAPG-to-partner and partner-to-CAPG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of actin polymerization or depolymerization grouped by CAPG-low versus CAPG-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPG→partner) and Y-score (partner→CAPG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of actin polymerization or depolymerization →	+0.067	+2.895	<.001	<.001	3	17
BONE	Negative regulation of actin filament depolymerization →	+0.207	+3.979	<.001	.001	3	16
BREAST	Actin filament capping →	+0.248	+3.236	<.001	<.001	3	16
OESOPHAGUS	Regulation of actin filament length →	+0.078	+2.313	<.001	<.001	3	15
BREAST	Regulation of actin filament polymerization →	+0.094	+3.292	<.001	<.001	2	16
BREAST	Negative regulation of actin filament polymerization →	+0.190	+3.986	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,255 associations by consensus.

Regulation of actin polymerization or depolymerization by CAPG expression — BREAST

Explore this box plot interactively →