CAP1

Across TCGA patient cohorts, CAP1 mutation is significantly associated with the RNA expression of many other genes, with 1,959 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CAP1-associated genes across cancer lineages are MTATP6P30, MTCO2P9, and RNU1-17P. Each is linked with CAP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CAP1-to-partner and partner-to-CAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTATP6P30 grouped by CAP1-low versus CAP1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAP1→partner) and Y-score (partner→CAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MTATP6P30 →	+0.147	+7.741	<.001	.009	3	2
BLCA	MTCO2P9 →	+0.030	+4.985	<.001	.002	3	2
UCEC	RNU1-17P →	+0.217	+2.543	<.001	<.001	3	2
BLCA	CRYAA →	+0.017	+3.713	<.001	.001	3	2
SKCM	LINC01810 →	+0.109	+7.816	<.001	.008	3	2
HNSC	RBM17P1 →	+0.197	+5.228	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,959 associations by consensus.

MTATP6P30 by CAP1 expression — COAD

Explore this box plot interactively →