CAP1

Across TCGA cell cohorts, CAP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,965 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CAP1-associated GO terms across cancer lineages are Retrograde transport, endosome to Golgi, Positive regulation of supramolecular fiber organization, and Endocytic recycling. Each is linked with CAP1 in more than 12 cancer types. Because this analysis shows association rather than direction, both CAP1-to-partner and partner-to-CAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Retrograde transport, endosome to Golgi grouped by CAP1-low versus CAP1-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CAP1→partner) and Y-score (partner→CAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Retrograde transport, endosome to Golgi →	+0.070	+0.691	<.001	<.001	3	13
LIVER	Positive regulation of supramolecular fiber organization →	+0.117	+0.998	<.001	.003	3	12
BONE	Endocytic recycling →	+0.097	+1.189	<.001	<.001	3	12
LIVER	Wound healing →	+0.136	+1.323	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Regulation of lamellipodium assembly →	+0.109	+0.803	.003	.008	2	13
LIVER	Caveola assembly →	+0.243	+1.051	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,965 associations by consensus.

Retrograde transport, endosome to Golgi by CAP1 expression — SKIN

Explore this box plot interactively →