CAND2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CAND2 protein abundance is significantly associated with the RNA expression of many other genes, with 8,876 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CAND2-associated genes across cancer lineages are ZNF728, LDB3, and PPP1R14A. Each is linked with CAND2 in more than 4 cancer types. Because this analysis shows association rather than direction, both CAND2-to-partner and partner-to-CAND2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CAND2 versus ZNF728 in OV, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAND2→partner) and Y-score (partner→CAND2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVZNF728 →+0.929+0.329.008.00535
HNSCLDB3 →+1.138+0.614<.001<.00135
CCRCCPPP1R14A →+0.864+0.357<.001<.00135
HNSCAPOD →+1.906+0.699<.001<.00135
UCECBEX2 →+1.959+0.501<.001<.00135
HNSCMYL3 →+1.267+0.609<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 8,876 associations by consensus.

CAND2 vs ZNF728 — OV

Per-sample scatter of CAND2 vs ZNF728 in OV (Pearson r = 0.32).

Explore this scatter interactively →

Exploration