CAND2

Across TCGA cell cohorts, CAND2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,061 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CAND2-associated GO terms across cancer lineages are Epigenetic regulation of gene expression, Negative regulation of gene expression, epigenetic, and Regulation of nucleotide-excision repair. Each is linked with CAND2 in more than 16 cancer types. Because this analysis shows association rather than direction, both CAND2-to-partner and partner-to-CAND2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epigenetic regulation of gene expression grouped by CAND2-low versus CAND2-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CAND2→partner) and Y-score (partner→CAND2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Epigenetic regulation of gene expression →	+0.048	+1.108	<.001	<.001	3	17
CNS	Negative regulation of gene expression, epigenetic →	+0.050	+1.104	<.001	<.001	3	15
STOMACH	Regulation of nucleotide-excision repair →	+0.141	+1.152	<.001	.004	3	14
BREAST	Regulation of mRNA splicing, via spliceosome →	+0.070	+0.584	<.001	.004	3	14
OVARY	Positive regulation of double-strand break repair via homologous recombination →	+0.070	+1.082	<.001	<.001	3	13
BREAST	Positive regulation of cell cycle →	+0.081	+0.837	<.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,061 associations by consensus.

Epigenetic regulation of gene expression by CAND2 expression — CNS

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