CAND1

Across TCGA patient cohorts, CAND1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,635 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CAND1-associated proteins across cancer lineages are PLCG2, ADNP, and FXR1. Each is linked with CAND1 in more than 5 cancer types. Because this analysis shows association rather than direction, both CAND1-to-partner and partner-to-CAND1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CAND1 versus PLCG2 in GBM, with a Pearson correlation of -0.27.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CAND1→partner) and Y-score (partner→CAND1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PLCG2 →	-0.608	-0.455	<.001	<.001	3	6
LSCC	ADNP →	+0.367	+0.420	<.001	<.001	3	6
LSCC	FXR1 →	+0.420	+0.510	<.001	<.001	3	6
UCEC	PPP1R10 →	+0.244	+0.463	<.001	<.001	3	5
LSCC	RASAL3 →	-0.485	-0.522	<.001	<.001	3	5
GBM	RBM12 →	+0.245	+0.306	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,635 associations by consensus.

CAND1 vs PLCG2 — GBM

Explore this scatter interactively →