CAND1

Across TCGA patient cohorts, CAND1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,742 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CAND1-associated genes across cancer lineages are DYRK2, BRAP, and CSRNP2. Each is linked with CAND1 in more than 5 cancer types. Because this analysis shows association rather than direction, both CAND1-to-partner and partner-to-CAND1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CAND1 versus DYRK2 in HNSC, with a Pearson correlation of 0.72.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAND1→partner) and Y-score (partner→CAND1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	DYRK2 →	+0.756	+0.421	<.001	.002	3	6
LSCC	BRAP →	+0.367	+0.199	<.001	<.001	3	5
PDAC	CSRNP2 →	+0.458	+0.214	<.001	<.001	3	5
BRCA	RAB5B →	+0.477	+0.155	<.001	<.001	3	5
OV	MDM1 →	+1.026	+0.468	<.001	<.001	3	5
OV	CNOT2 →	+0.802	+0.501	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,742 associations by consensus.

CAND1 vs DYRK2 — HNSC

Explore this scatter interactively →