CAND1

Across TCGA cell cohorts, CAND1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,622 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CAND1-associated GO terms across cancer lineages are Heterochromatin organization, Heterochromatin formation, and Centrosome duplication. Each is linked with CAND1 in more than 17 cancer types. Because this analysis shows association rather than direction, both CAND1-to-partner and partner-to-CAND1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Heterochromatin organization grouped by CAND1-low versus CAND1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CAND1→partner) and Y-score (partner→CAND1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Heterochromatin organization →	+0.073	+0.843	<.001	<.001	3	18
SOFT_TISSUE	Heterochromatin formation →	+0.075	+0.835	<.001	<.001	3	18
LUNG_SCLC	Centrosome duplication →	+0.107	+0.753	<.001	<.001	3	17
SOFT_TISSUE	Negative regulation of gene expression, epigenetic →	+0.071	+1.015	<.001	<.001	3	17
LUNG_SCLC	Regulation of microtubule-based process →	+0.088	+0.750	<.001	<.001	3	17
OVARY	Epigenetic regulation of gene expression →	+0.068	+0.782	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,622 associations by consensus.

Heterochromatin organization by CAND1 expression — SOFT_TISSUE

Explore this box plot interactively →