CAMTA2

Across TCGA patient cohorts, CAMTA2 mutation is significantly associated with the total protein of many other genes, with 51 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CAMTA2-associated genes across cancer lineages are PCNA, Chk2_pT68, and ATM. Each is linked with CAMTA2 in more than 3 cancer types. Because this analysis shows association rather than direction, both CAMTA2-to-partner and partner-to-CAMTA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCNA grouped by CAMTA2-low versus CAMTA2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAMTA2→partner) and Y-score (partner→CAMTA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCNA →	+0.181	+1.378	.004	.008	3	4
BLCA	Chk2_pT68 →	-0.177	-2.949	.014	.034	3	3
UCEC	ATM →	-0.543	-1.807	<.001	<.001	3	3
UCEC	ERK2 →	+0.194	+1.584	<.001	.002	3	2
UCEC	mTOR_pS2448 →	-0.152	-1.807	<.001	<.001	3	2
UCEC	Annexin-1 →	+0.368	+1.785	.019	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 51 associations by consensus.

PCNA by CAMTA2 expression — UCEC

Explore this box plot interactively →