CAMSAP3

Across TCGA pan-cancer cohorts, CAMSAP3 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated CAMSAP3 data layer compared with 24 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher CAMSAP3 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated CAMSAP3 expression acts as an unfavorable survival marker, although some lineages such as LSCC and PDAC show a favorable association.

LSCC, PDAC, and COAD are the cancer types where CAMSAP3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Median	II,III,IV	0.864	0.521	<.001	54	view →
PDAC	OS	Quartile	III,IV	0.672	0.212	.003	34	view →
COAD	DFS	Median	II,III,IV	1.000	0.892	.039	24	view →
CCRCC	DFS	Median	II,III,IV	0.957	0.780	.015	18	view →
LUAD	OS	Tertile	III,IV	0.713	0.259	.003	15	view →
GBM	DFS	Quartile	All	0.908	0.637	.004	10	view →
UCEC	DFS	Quartile	II,III,IV	0.893	0.351	.023	4	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

CAMSAP3–LSCC (DFS)

Open the LSCC breakdown →