CAMSAP3

Across TCGA patient cohorts, CAMSAP3 mutation is significantly associated with the total protein of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CAMSAP3-associated genes across cancer lineages are MSH6, p90 RSK, and Rad50. Each is linked with CAMSAP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CAMSAP3-to-partner and partner-to-CAMSAP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MSH6 grouped by CAMSAP3-low versus CAMSAP3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAMSAP3→partner) and Y-score (partner→CAMSAP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MSH6 →	-0.479	-2.392	<.001	<.001	3	2
UCEC	p90 RSK →	+0.134	+1.543	.020	.002	3	2
UCEC	Rad50 →	-0.167	-1.321	.022	.012	3	2
UCEC	Caspase-7-cleavedD198 →	+0.374	+1.700	.037	.040	3	2
UCEC	Cyclin-B1 →	+0.437	+2.321	.010	.005	3	2
COAD	GSK-3_pS9 →	-0.394	-3.169	.020	.018	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

MSH6 by CAMSAP3 expression — UCEC

Explore this box plot interactively →