CAMSAP3

Across TCGA cell cohorts, CAMSAP3 mutation is significantly associated with the RNA expression of many other genes, with 1,819 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CAMSAP3-associated genes across cancer lineages are RAD51, CNOT7, and DOCK3. Each is linked with CAMSAP3 in more than 2 cancer types. Because this analysis shows association rather than direction, both CAMSAP3-to-partner and partner-to-CAMSAP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RAD51 grouped by CAMSAP3-low versus CAMSAP3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAMSAP3→partner) and Y-score (partner→CAMSAP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	RAD51 →	+0.573	+2.158	<.001	.004	3	3
LARGE_INTESTINE	CNOT7 →	+0.550	+3.237	.004	.003	3	2
SKIN	DOCK3 →	+0.600	+3.588	<.001	<.001	3	2
BLOOD_Leukemia	OR13J1 →	+0.159	+3.607	<.001	.004	3	2
LARGE_INTESTINE	USP14 →	+0.741	+3.409	<.001	<.001	3	2
LARGE_INTESTINE	CEP76 →	+0.680	+2.158	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,819 associations by consensus.

RAD51 by CAMSAP3 expression — LARGE_INTESTINE

Explore this box plot interactively →