CAMSAP2

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CAMSAP2 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CAMSAP2 data layer compared with 25 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher CAMSAP2 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated CAMSAP2 expression acts as an unfavorable survival marker, although some lineages such as GBM and HNSC show a favorable association.

CCRCC, LSCC, and GBM are the cancer types where CAMSAP2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CCRCCOSMedianII,III,IV0.7170.897.01115view →
LSCCDFSMedianAll0.6000.791.0169view →
GBMDFSQuartileAll0.8750.658.0156view →
HNSCDFSQuartileII,III,IV1.0000.901.0213view →
PDACOSQuartileII,III,IV0.3570.565.0492view →
Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CAMSAP2–CCRCC (OS)

Kaplan–Meier survival curve for CAMSAP2 mass-spec protein-high vs -low samples in CCRCC.

Open the CCRCC breakdown →

Exploration