CAMSAP2

Across TCGA cell cohorts, CAMSAP2 mutation is significantly associated with the RNA expression of many other genes, with 348 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CAMSAP2-associated genes across cancer lineages are ADPRM, MRPS18A, and FOXN1. Each is linked with CAMSAP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CAMSAP2-to-partner and partner-to-CAMSAP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ADPRM grouped by CAMSAP2-low versus CAMSAP2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAMSAP2→partner) and Y-score (partner→CAMSAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ADPRM →	+0.456	+2.526	.008	.002	3	2
LARGE_INTESTINE	MRPS18A →	+0.283	+2.526	.006	.002	3	2
SKIN	FOXN1 →	+0.395	+2.994	<.001	.006	3	1
SKIN	ZAN →	+0.002	+3.700	<.001	.009	3	1
SKIN	AKAP14 →	+0.117	+3.115	.008	.004	3	1
SKIN	CYP2A13 →	+0.031	+3.562	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 348 associations by consensus.

ADPRM by CAMSAP2 expression — LARGE_INTESTINE

Explore this box plot interactively →