CAMSAP1

Across TCGA patient cohorts, CAMSAP1 mutation is significantly associated with the total protein of many other genes, with 76 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CAMSAP1-associated genes across cancer lineages are HER3_pY1289, C-Raf, and GAPDH. Each is linked with CAMSAP1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CAMSAP1-to-partner and partner-to-CAMSAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HER3_pY1289 grouped by CAMSAP1-low versus CAMSAP1-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAMSAP1→partner) and Y-score (partner→CAMSAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HER3_pY1289 →	+0.203	+2.827	.031	.036	3	5
COAD	C-Raf →	+0.182	+2.330	.005	.020	3	5
COAD	GAPDH →	+0.835	+2.820	<.001	.035	3	4
UCEC	Di-Ras3 →	-0.096	-2.401	.020	.002	3	4
COAD	Caspase-7-cleavedD198 →	+1.919	+3.016	<.001	.018	3	3
COAD	PKC-a →	-0.489	-3.000	<.001	.034	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 76 associations by consensus.

HER3_pY1289 by CAMSAP1 expression — BRCA

Explore this box plot interactively →