CAMP

Across TCGA patient cohorts, CAMP protein abundance is significantly associated with the RNA expression of many other genes, with 16,316 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CAMP-associated genes across cancer lineages are ADGRE3, FCGR3B, and CXCR1. Each is linked with CAMP in more than 9 cancer types. Because this analysis shows association rather than direction, both CAMP-to-partner and partner-to-CAMP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CAMP versus ADGRE3 in LSCC, with a Pearson correlation of 0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAMP→partner) and Y-score (partner→CAMP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ADGRE3 →	+0.898	+1.540	<.001	<.001	3	10
LSCC	FCGR3B →	+1.923	+1.587	<.001	<.001	3	10
LSCC	CXCR1 →	+1.433	+1.677	<.001	<.001	3	10
LSCC	CXCL1 →	+2.240	+1.400	<.001	<.001	3	10
HNSC	CLEC4D →	+0.650	+0.964	<.001	<.001	3	10
LUAD	CXCL8 →	+2.705	+1.577	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,316 associations by consensus.

CAMP vs ADGRE3 — LSCC

Explore this scatter interactively →