CAMP

Across TCGA cell cohorts, CAMP RNA expression is significantly associated with the go_rna of many other GO terms, with 3,063 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CAMP-associated GO terms across cancer lineages are Positive regulation of antimicrobial humoral response, Cellular response to peptidoglycan, and Negative regulation of protein localization to cell periphery. Each is linked with CAMP in more than 8 cancer types. Because this analysis shows association rather than direction, both CAMP-to-partner and partner-to-CAMP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of antimicrobial humoral response grouped by CAMP-low versus CAMP-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CAMP→partner) and Y-score (partner→CAMP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Positive regulation of antimicrobial humoral response →	+1.016	+2.029	<.001	<.001	3	9
SKIN	Cellular response to peptidoglycan →	-0.252	-0.652	<.001	<.001	3	6
BLOOD_Leukemia	Negative regulation of protein localization to cell periphery →	+0.053	+0.763	<.001	<.001	3	6
LARGE_INTESTINE	Negative regulation of protein localization to membrane →	+0.061	+0.198	.002	.004	2	6
BREAST	Mitotic spindle assembly checkpoint signaling →	-0.164	-1.748	<.001	<.001	3	5
BREAST	Spindle assembly checkpoint signaling →	-0.164	-1.748	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,063 associations by consensus.

Positive regulation of antimicrobial humoral response by CAMP expression — BLOOD_Lymphoma

Explore this box plot interactively →