CAMLG

Across TCGA pan-cancer cohorts, CAMLG mass-spec protein differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of CAMLG’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where CAMLG mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types CAMLG is over-expressed in tumor, although a few such as HNSC and PDAC show the opposite, repressed pattern.

LUAD, HNSC, and CCRCC are the cancer types where CAMLG tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CAMLG mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	II,III,IV	+0.356	<.001	8	view →
HNSC	All	All	−0.136	.007	6	view →
CCRCC	All	All	+0.125	.006	5	view →
LSCC	Male	III,IV	+0.158	.025	3	view →
PDAC	Male	All	−0.244	.034	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

CAMLG–LUAD

Open the LUAD breakdown →