Across TCGA pan-cancer cohorts, CAMKMT mass-spec protein differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of CAMKMT’s most consistent transcriptional readouts.
The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where CAMKMT mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types CAMKMT is over-expressed in tumor.
PDAC and LSCC are the cancer types where CAMKMT tumor–normal differential expression is most reproducible.