CAMKMT

Across TCGA patient cohorts, CAMKMT mutation is significantly associated with the total protein of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CAMKMT-associated genes across cancer lineages are EGFR, MEK1, and ATM. Each is linked with CAMKMT in more than 1 cancer types. Because this analysis shows association rather than direction, both CAMKMT-to-partner and partner-to-CAMKMT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EGFR grouped by CAMKMT-low versus CAMKMT-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAMKMT→partner) and Y-score (partner→CAMKMT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR →	-0.169	-3.321	.012	.010	3	1
UCEC	MEK1 →	+0.436	+2.906	.004	.001	3	1
UCEC	ATM →	-0.464	-1.700	.015	.044	3	1
UCEC	4E-BP1_pT37_T46 →	-0.545	-3.446	<.001	.005	3	1
UCEC	Caspase-7-cleavedD198 →	+0.605	+3.341	.016	.005	3	1
UCEC	Caspase-8 →	-0.249	-2.222	.019	.011	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

EGFR by CAMKMT expression — UCEC

Explore this box plot interactively →