CAMKMT

Across TCGA cell cohorts, CAMKMT mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CAMKMT-associated genes across cancer lineages are SULT6B1, ASB17, and SYNPO2L. Each is linked with CAMKMT in more than 1 cancer types. Because this analysis shows association rather than direction, both CAMKMT-to-partner and partner-to-CAMKMT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SULT6B1 grouped by CAMKMT-low versus CAMKMT-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAMKMT→partner) and Y-score (partner→CAMKMT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SULT6B1 →	+0.032	+3.977	<.001	.001	3	2
LARGE_INTESTINE	ASB17 →	+0.015	+3.632	<.001	.003	3	1
LARGE_INTESTINE	SYNPO2L →	+0.266	+3.415	<.001	.009	3	1
LARGE_INTESTINE	GPR171 →	+0.013	+3.688	.004	.002	3	1
LARGE_INTESTINE	SERPINA11 →	+0.072	+3.196	<.001	.007	3	1
LARGE_INTESTINE	PRAMEF33 →	+0.076	+4.022	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

SULT6B1 by CAMKMT expression — LARGE_INTESTINE

Explore this box plot interactively →