CAMKK1

Across TCGA cell cohorts, CAMKK1 mutation is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CAMKK1-associated genes across cancer lineages are OR10AG1, IFNA2, and SEMG2. Each is linked with CAMKK1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CAMKK1-to-partner and partner-to-CAMKK1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10AG1 grouped by CAMKK1-low versus CAMKK1-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAMKK1→partner) and Y-score (partner→CAMKK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	OR10AG1 →	+0.013	+5.169	<.001	.005	3	1
BREAST	IFNA2 →	+0.022	+5.169	<.001	.005	3	1
LARGE_INTESTINE	SEMG2 →	+0.393	+2.878	.006	.009	3	1
LARGE_INTESTINE	MSGN1 →	+0.107	+3.760	<.001	<.001	3	1
LARGE_INTESTINE	FANCD2OS →	+0.142	+3.667	<.001	.003	3	1
LARGE_INTESTINE	TBC1D21 →	+0.008	+3.700	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

OR10AG1 by CAMKK1 expression — BREAST

Explore this box plot interactively →