CAMK4

Across TCGA pan-cancer cohorts, CAMK4 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CAMK4 data layer compared with 25 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher CAMK4 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated CAMK4 expression acts as an unfavorable survival marker, although some lineages such as PDAC and LUAD show a favorable association.

PDAC, LUAD, and GBM are the cancer types where CAMK4 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Quartile	All	0.678	0.380	<.001	48	view →
LUAD	DFS	Median	All	0.972	0.653	.010	15	view →
GBM	DFS	Quartile	All	0.896	0.581	.002	10	view →
CCRCC	DFS	Quartile	III,IV	0.801	0.355	.017	6	view →
LSCC	OS	Quartile	II,III,IV	0.568	0.917	.018	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CAMK4–PDAC (OS)

Open the PDAC breakdown →