CAMK4

Across TCGA patient cohorts, CAMK4 mutation is significantly associated with the RNA expression of many other genes, with 3,805 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CAMK4-associated genes across cancer lineages are LDHAP7, IMP3P2, and RNU2-27P. Each is linked with CAMK4 in more than 2 cancer types. Because this analysis shows association rather than direction, both CAMK4-to-partner and partner-to-CAMK4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LDHAP7 grouped by CAMK4-low versus CAMK4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAMK4→partner) and Y-score (partner→CAMK4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LDHAP7 →	+0.630	+3.008	.001	<.001	3	3
UCEC	IMP3P2 →	+0.184	+1.814	<.001	.001	3	3
UCEC	RNU2-27P →	+0.672	+2.103	.002	.003	3	3
UCEC	METTL4 →	+0.367	+3.757	.004	<.001	3	3
UCEC	ENO2 →	+0.918	+2.662	<.001	<.001	3	3
UCEC	AUNIP →	+0.672	+2.914	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,805 associations by consensus.

LDHAP7 by CAMK4 expression — UCEC

Explore this box plot interactively →