CAMK4

Across TCGA cell cohorts, CAMK4 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,037 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CAMK4-associated GO terms across cancer lineages are Regulation of chromosome organization, Centrosome cycle, and Positive regulation of chromosome organization. Each is linked with CAMK4 in more than 12 cancer types. Because this analysis shows association rather than direction, both CAMK4-to-partner and partner-to-CAMK4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of chromosome organization grouped by CAMK4-low versus CAMK4-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CAMK4→partner) and Y-score (partner→CAMK4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of chromosome organization →	+0.080	+0.949	.002	<.001	3	13
LUNG_SCLC	Centrosome cycle →	+0.083	+2.107	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Positive regulation of chromosome organization →	+0.070	+0.832	.003	.001	3	12
UPPER_AERODIGESTIVE_TRACT	Mitotic spindle organization →	+0.082	+0.850	.004	.002	3	11
URINARY_TRACT	Mitotic spindle assembly checkpoint signaling →	+0.141	+1.404	<.001	<.001	3	11
URINARY_TRACT	Spindle assembly checkpoint signaling →	+0.141	+1.404	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,037 associations by consensus.

Regulation of chromosome organization by CAMK4 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →