Across TCGA pan-cancer cohorts, CAMK2G RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of CAMK2G’s most consistent transcriptional readouts.
The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where CAMK2G RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CAMK2G is over-expressed in tumor, although a few such as KICH and COAD show the opposite, repressed pattern.
LIHC, KICH, and COAD are the cancer types where CAMK2G tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CAMK2G RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.