CAMK2G

Across TCGA pan-cancer cohorts, CAMK2G mass-spec protein differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of CAMK2G’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where CAMK2G mass-spec protein is repressed in tumor relative to normal tissue. In most cancer types CAMK2G is over-expressed in tumor, although a few such as COAD and CCRCC show the opposite, repressed pattern.

COAD, CCRCC, and PDAC are the cancer types where CAMK2G tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CAMK2G mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Male	III,IV	−1.566	<.001	11	view →
CCRCC	Male	All	−0.680	<.001	11	view →
PDAC	Female	II,III,IV	+0.738	<.001	8	view →
LSCC	Female	All	−0.512	<.001	8	view →
HNSC	Male	IV	−0.504	<.001	8	view →
LUAD	Male	III,IV	−0.370	<.001	8	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

CAMK2G–COAD

Open the COAD breakdown →