CAMK2B

Across TCGA patient cohorts, CAMK2B mutation is significantly associated with the total protein of many other genes, with 38 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CAMK2B-associated genes across cancer lineages are TFRC, eEF2, and ACC1. Each is linked with CAMK2B in more than 2 cancer types. Because this analysis shows association rather than direction, both CAMK2B-to-partner and partner-to-CAMK2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TFRC grouped by CAMK2B-low versus CAMK2B-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAMK2B→partner) and Y-score (partner→CAMK2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	TFRC →	+0.690	+2.584	.007	.011	3	3
UCEC	eEF2 →	+0.407	+1.807	.001	.024	3	2
UCEC	ACC1 →	+0.268	+1.750	.033	.049	3	2
UCEC	JNK2 →	+0.260	+3.009	<.001	<.001	3	2
UCEC	ATM →	-0.610	-4.074	<.001	<.001	3	2
UCEC	Collagen-VI →	-0.185	-2.446	.009	.018	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

TFRC by CAMK2B expression — SKCM

Explore this box plot interactively →