CAMK1G

Across TCGA patient cohorts, CAMK1G mutation is significantly associated with the total protein of many other genes, with 26 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CAMK1G-associated genes across cancer lineages are Paxillin, PKC-a, and Smad3. Each is linked with CAMK1G in more than 1 cancer types. Because this analysis shows association rather than direction, both CAMK1G-to-partner and partner-to-CAMK1G results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Paxillin grouped by CAMK1G-low versus CAMK1G-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAMK1G→partner) and Y-score (partner→CAMK1G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Paxillin →	+0.291	+2.817	.020	.036	3	1
UCEC	PKC-a →	+0.462	+3.183	.018	.009	3	1
UCEC	Smad3 →	+0.159	+3.169	.029	.019	3	1
UCEC	Src_pY416 →	-0.290	-2.446	.012	.020	3	1
UCEC	VHL →	-1.261	-2.459	<.001	.020	3	1
UCEC	14-3-3_beta →	-0.108	-2.973	.026	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

Paxillin by CAMK1G expression — UCEC

Explore this box plot interactively →