CAMK1D

Across TCGA patient cohorts, CAMK1D mutation is significantly associated with the total protein of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CAMK1D-associated genes across cancer lineages are 4E-BP1, PCNA, and VHL. Each is linked with CAMK1D in more than 3 cancer types. Because this analysis shows association rather than direction, both CAMK1D-to-partner and partner-to-CAMK1D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 4E-BP1 grouped by CAMK1D-low versus CAMK1D-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAMK1D→partner) and Y-score (partner→CAMK1D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	4E-BP1 →	+0.360	+3.489	<.001	.002	3	4
UCEC	PCNA →	+0.235	+2.584	.005	.010	3	2
UCEC	VHL →	-0.611	-2.000	.021	.030	3	2
UCEC	Caspase-7-cleavedD198 →	+0.566	+3.604	.015	.001	3	2
UCEC	Caspase-8 →	-0.285	-2.502	.003	.002	3	2
SKCM	Heregulin →	+0.138	+1.887	.040	.029	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

4E-BP1 by CAMK1D expression — UCEC

Explore this box plot interactively →