CAMK1

Across TCGA patient cohorts, CAMK1 mutation is significantly associated with the total protein of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CAMK1-associated genes across cancer lineages are ASNS, eIF4E, and JNK2. Each is linked with CAMK1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CAMK1-to-partner and partner-to-CAMK1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by CAMK1-low versus CAMK1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAMK1→partner) and Y-score (partner→CAMK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.459	+3.169	.004	.019	3	2
UCEC	eIF4E →	+0.197	+2.700	.038	.006	3	1
UCEC	JNK2 →	+0.303	+2.700	<.001	.006	3	1
UCEC	MEK1 →	+0.493	+3.700	.002	.001	3	1
UCEC	p62 Lck ligand →	+0.399	+3.331	.006	.005	3	1
UCEC	PDK1_pS241 →	+0.171	+3.321	.026	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

ASNS by CAMK1 expression — UCEC

Explore this box plot interactively →