CALU

Across TCGA patient cohorts, CALU protein abundance is significantly associated with the RNA expression of many other genes, with 18,129 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CALU-associated genes across cancer lineages are LGALS1, POSTN, and GPX8. Each is linked with CALU in more than 6 cancer types. Because this analysis shows association rather than direction, both CALU-to-partner and partner-to-CALU results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CALU versus LGALS1 in LSCC, with a Pearson correlation of 0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CALU→partner) and Y-score (partner→CALU) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	LGALS1 →	+0.918	+0.372	<.001	<.001	3	7
GBM	POSTN →	+2.497	+0.440	.002	.002	3	7
GBM	GPX8 →	+1.148	+0.482	<.001	<.001	3	7
BRCA	CTHRC1 →	+1.178	+0.494	<.001	<.001	3	7
GBM	TMEM45A →	+1.030	+0.517	<.001	<.001	3	7
GBM	LINC01614 →	+1.302	+0.552	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,129 associations by consensus.

CALU vs LGALS1 — LSCC

Explore this scatter interactively →