CALU

Across TCGA cell cohorts, CALU RNA expression is significantly associated with the go_rna of many other GO terms, with 6,208 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CALU-associated GO terms across cancer lineages are Positive regulation of protein exit from endoplasmic reticulum, COPII-coated vesicle cargo loading, and Maintenance of protein location in cell. Each is linked with CALU in more than 19 cancer types. Because this analysis shows association rather than direction, both CALU-to-partner and partner-to-CALU results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein exit from endoplasmic reticulum grouped by CALU-low versus CALU-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CALU→partner) and Y-score (partner→CALU) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Positive regulation of protein exit from endoplasmic reticulum →	+0.159	+1.587	.003	<.001	3	20
CNS	COPII-coated vesicle cargo loading →	+0.137	+1.599	<.001	<.001	3	16
BONE	Maintenance of protein location in cell →	+0.154	+2.559	<.001	<.001	3	16
OESOPHAGUS	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.120	+1.615	<.001	<.001	3	16
BONE	Maintenance of protein localization in organelle →	+0.140	+1.965	.001	.002	3	15
SKIN	Vesicle cargo loading →	+0.143	+1.475	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,208 associations by consensus.

Positive regulation of protein exit from endoplasmic reticulum by CALU expression — OESOPHAGUS

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